AB-2980 NIR-CLA

The novel probe for detection of active oxygen is emitted near-infrared light of 800nm by reaction with superoxide.

Monitoring of active oxygen in human blood. It detected amount of O2- generated by stimulation with zymosan against human blood sample in using NIR-CLA, MCLA and Luminol.

 

Monitoring of active oxygen in human blood
It detected amount of O2- generated by stimulation with zymozan against human blood sample in using NIR-CLA, MCLA and Luminol.

Purpose and Application

Detection of active oxygen.

Features
The novel probe for detection of active oxygen is emitted near-infrared light of 800nm by reaction with superoxide.

Since hemoglobin absorbs the light below 650nm, other probes such as MCLA or Luminol which has a peak in under 500nm can not be detected their signals in blood sample.
NIR-CLA probe enables to detect superoxide in whole blood sample very efficiently. The signal of NIR-CLA probe in blood sample is transmitted abount 20% of that in PBS, although it is affected from absorption by hemoglobin.

Specifications
Product Number AB-2980
Product Name NIR-CLA
(Near-infrared probe for active oxygen detection)
Substance Indocyanine Imidazopyrazinone compound
Molecular weight 1156 Dalton
Wavelength 800 nm
Amount 0.1 mg  (powder)
Storage -80°C

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